Hello! I am an incoming PhD student in the Department of Biomedical Data Science at Stanford University. I am currently a computational research lab manager in the Rabadan Lab at the Columbia University Irving Medical Center. Previously I was a research engineer in the Clinical Machine Learning Group at MIT CSAIL and a data scientist at Microsoft New England. I completed my bachelor's degree at Columbia University in mathematics and computer science in 2019, during which I was fortunate to be advised by Daniel Hsu.

I am currently interested in computational genomics and the development of large-scale foundation models for biological applications, particularly models pretrained on DNA sequences and the epigenome, and the application of these models to understanding disease mechanism at the single cell level. In my current work, I am fortunate to be advised by Raul Rabadan and develop deep learning methods to predict the mutational evolution of viral protein sequences.

I am passionate about diversity and inclusion in the tech, AI, and medical communities, both in regards to patient access to care and on the side of AI researchers and scientific development. At Microsoft New England, I co-founded and led a Diversity Recruiting Initiative with Ehi Nosakhare targeting the recruitment of underrepresented minorities for entry-level AI positions, an effort that I am particularly excited about.

Selected Publications

A deep dive into single-cell RNA sequencing foundation models
Rebecca Boiarsky, Nalini Singh, Alejandro Buendia, Gad Getz, David Sontag Machine Learning in Computational Biology (MLCB 2023), Nov. 2023 (Oral Presentation, Top 15%)
abstract| pdf

GET: A foundation model of transcription across human cell types
Xi Fu, Shentong Mo, Anqi Shao, Anouchka Laurent, Alejandro Buendia, Adolfo A. Ferrando, Alberto Ciccia, Yanyan Lan, Teresa Palomero, David M. Owens, Eric P. Xing, Raul Rabadan bioRxiv 2023.09.24.559168, Sept. 2023
abstract| pdf

TabLLM: Few-shot classification of tabular data with large language models
Stefan Hegselmann, Alejandro Buendia, Hunter Lang, Monica Agrawal, Xiaoyi Jiang, David Sontag 26th International Conference on Artificial Intelligence and Statistics (AISTATS 2023), Apr. 2023
abstract| pdf

Examination and extension of strategies for improving personalized language modeling via interpolation
Liqun Shao, Sahitya Mantravadi, Tom Manzini, Alejandro Buendia, Manon Knoertzer, Soundar Srinivasan, Chris Quirk
First Workshop on Natural Language Interfaces (ACL 2020), July 2020
abstract| pdf

Random walk fundamental tensor and graph importance measures
Daniel Boley, Alejandro Buendia International Workshop on Big Social Media Data Management and Analysis (IJCAI 2019), Aug. 2019
talk| pdf

Optimized graph-based trust mechanisms using hitting times
Alejandro Buendia, Daniel Boley International Workshop on Trust in Agent Societies (AAMAS 2017), May 2017
abstract| pdf